Education only · provider review required
TB-500 · Wound-healing research context
A thymosin beta-4 fragment discussed in tissue-repair research — almost entirely preclinical.
Medically reviewed by Bernard Garcia, MD
What it is
TB-500 is a synthetic fragment of thymosin beta-4, a naturally occurring protein involved in cell migration and actin regulation. It is discussed in wound-healing, cardiac and soft-tissue research and is frequently paired with BPC-157 in online discussion.
Most published work is in cells and animals. Full-length thymosin beta-4 has reached small human trials for specific indications; TB-500 as sold online is a different, unregulated product.
How it works
Research describes effects on cell migration, blood-vessel formation and inflammation signalling in laboratory models. These are proposed mechanisms in animals and tissue, not demonstrated effects in people.
Research status
| Research area | Status |
|---|---|
| Soft-tissue and wound repair | Preclinical (animal models) |
| Cardiac tissue research | Preclinical · early human for full-length Tβ4 |
| Human clinical trials of TB-500 | None published |
| Regulatory status (US FDA) | Not an FDA-approved drug · WADA-prohibited |
Status reflects published research context only and is not a statement of safety, efficacy, or suitability for any person.
Is it legal?
In the United States this compound is not an FDA-approved drug for any use. It is not lawfully sold for human use as a "research chemical", and whether a licensed provider can consider it depends on federal compounding rules and state law, both of which change. This is a general note, not legal advice.
TB-500 is on the World Anti-Doping Agency prohibited list.
Frequently asked questions
Is TB-500 the same as thymosin beta-4?
No. TB-500 is a synthetic fragment; thymosin beta-4 is the full protein. Studies of one do not automatically apply to the other.
Is it banned in sport?
Yes — it appears on the WADA prohibited list. If you compete in a tested sport, that is decisive.
Why is it always mentioned with BPC-157?
Both are discussed in soft-tissue research and marketed together online. Our comparison page walks through the published context for each without treating either as a treatment.
Next step
Next step: a 3-minute confidential intake, reviewed by a licensed provider. No treatment is promised or implied.
Free · about 10 minutes · reviewed by a licensed physician
General education · Not medical advice · Provider approval required