Education only · provider review required

Kisspeptin · Reproductive-endocrinology research

A natural signalling peptide studied for its role in the hormonal axis — human research, no approval.

Medically reviewed by Bernard Garcia, MD

What it is

Kisspeptin is a peptide produced in the hypothalamus that signals the release of gonadotropin-releasing hormone (GnRH), which in turn drives LH, FSH and sex-hormone production. Because it sits at the top of the reproductive hormone axis, it has been studied in fertility, hypogonadism and, more recently, sexual-function research.

It is one of the better-studied research peptides in humans — but as a research tool and diagnostic candidate, not as an approved medicine.

How it works

Human studies have used kisspeptin infusions or injections to trigger hormone release in controlled settings: ovulation induction in IVF research, testing of the hormonal axis, and small studies of brain response to sexual stimuli. Effects are short-lived and dose-dependent, and the studies are small.

Research status

Research area Status
Reproductive hormone axis (GnRH, LH, FSH) Human physiology studies
Fertility / IVF research Early human trials
Sexual-function research Small human imaging studies
Regulatory status (US FDA) Not an FDA-approved drug

Status reflects published research context only and is not a statement of safety, efficacy, or suitability for any person.

Frequently asked questions

Is kisspeptin a hormone or a peptide?

Both, in the everyday sense: it is a peptide that acts as a signalling hormone in the brain.

Is it used in fertility clinics?

It has been studied as a trigger in IVF research, but it is not an approved fertility medicine and is not routine clinical practice.

Does this site describe how it is used?

No. Vitrex publishes no dosing or protocols for any substance.

Next step

Next step: a 3-minute confidential intake, reviewed by a licensed provider. No treatment is promised or implied.

Discuss with a provider

Free · about 10 minutes · reviewed by a licensed physician

General education · Not medical advice · Provider approval required