Education only · provider review required
DHEA · Supplement on the shelf, prescription in the clinic
A hormone precursor sold over the counter — and one approved prescription form.
Medically reviewed by Bernard Garcia, MD
What it is
DHEA (dehydroepiandrosterone) is an adrenal hormone precursor. In the US it is sold as a dietary supplement, while a prescription vaginal form (prasterone, Intrarosa) is FDA-approved for painful intercourse due to menopause.
Evidence for oral DHEA in ageing, mood, libido or body composition is mixed and mostly small-scale.
How it works
DHEA converts to androgens and oestrogens in tissue. Because it is a hormone precursor, it can affect hormone-sensitive conditions, which is why it warrants a provider conversation despite being over the counter.
Research status
| Research area | Status |
|---|---|
| Menopausal dyspareunia (vaginal prasterone) | FDA-approved |
| Oral DHEA for ageing / mood / libido | Mixed small studies |
| Adrenal insufficiency adjunct | Studied · not approved |
| Sport | WADA-prohibited |
Status reflects published research context only and is not a statement of safety, efficacy, or suitability for any person.
Is it legal?
Oral DHEA is a dietary supplement in the US (and banned in sport by WADA); prasterone is FDA-approved for a specific indication. This is a general note, not legal advice.
Frequently asked questions
If it is a supplement, why ask a provider?
Because it becomes sex hormones in the body and can affect hormone-sensitive conditions.
Is it banned in sport?
Yes.
Is it a peptide?
No — a steroid hormone precursor. Listed because it is researched alongside hormonal-pathway peptides.
Next step
Next step: a 3-minute confidential intake, reviewed by a licensed provider. No treatment is promised or implied.
Free · about 10 minutes · reviewed by a licensed physician
General education · Not medical advice · Provider approval required