Education only · provider review required
5-Amino-1MQ · A small molecule, not a peptide, in preclinical research
An NNMT inhibitor studied in mice and sold online as a "fat-loss" compound.
Medically reviewed by Bernard Garcia, MD
What it is
5-Amino-1MQ is a small synthetic molecule (not a peptide) that inhibits the enzyme NNMT, which is involved in cellular energy metabolism. It is discussed in metabolic and body-composition contexts because of mouse studies published from around 2018.
There are no published human trials. It is included here because it is sold in the same channels as peptides and people ask.
How it works
In mouse models, NNMT inhibition altered fat-cell metabolism and reduced fat mass. Whether the mechanism operates the same way in humans, and at what safety cost, is unknown.
Research status
| Research area | Status |
|---|---|
| Fat metabolism (mouse models) | Preclinical |
| Muscle and metabolic research | Preclinical |
| Human clinical trials | None published |
| Regulatory status (US FDA) | Not an FDA-approved drug |
Status reflects published research context only and is not a statement of safety, efficacy, or suitability for any person.
Is it legal?
In the United States this compound is not an FDA-approved drug for any use. It is not lawfully sold for human use as a "research chemical", and whether a licensed provider can consider it depends on federal compounding rules and state law, both of which change. This is a general note, not legal advice.
Frequently asked questions
Is 5-Amino-1MQ a peptide?
No — it is a small molecule. It is listed here because of how it is marketed.
Is there any human evidence?
No published human trials as of the last review.
Why is it on a compliance-focused site?
So that the honest evidence status is easy to find next to the marketing.
Next step
Next step: a 3-minute confidential intake, reviewed by a licensed provider. No treatment is promised or implied.
Free · about 10 minutes · reviewed by a licensed physician
General education · Not medical advice · Provider approval required