Solo educación · requiere revisión profesional
Metformin · Diabetes medicine, longevity conversation
A cheap, approved medicine with a large trial asking whether it slows ageing.
Revisado médicamente por Bernard Garcia, MD
Qué es
Metformin is FDA-approved for type 2 diabetes and is among the most prescribed medicines in the world. Observational data and the planned TAME trial have made it central to longevity discussion; whether it delays age-related disease in non-diabetic people is unproven.
Cómo funciona
Metformin lowers hepatic glucose output and improves insulin sensitivity; proposed ageing-related mechanisms include AMPK activation. Off-label use in healthy adults has trade-offs, including possible blunting of exercise adaptations in some studies.
Estado de la investigación
| Área de investigación | Estado |
|---|---|
| Type 2 diabetes | FDA-approved |
| Prediabetes | Guideline-supported off-label |
| Longevity in non-diabetic adults | Unproven · TAME trial planned |
| PCOS | Off-label · commonly used |
El estado refleja únicamente el contexto de la investigación publicada y no constituye una afirmación de seguridad, eficacia o idoneidad para ninguna persona.
¿Es legal?
Metformin is FDA-approved for type 2 diabetes; use for longevity is off-label. This is a general note, not legal advice.
Preguntas frecuentes
Should healthy people take metformin?
That is exactly the question the evidence has not answered. A provider weighs it individually.
Why is it on a peptide site?
It is researched alongside metabolic and longevity peptides, and readers ask.
Is it a peptide?
No — a small-molecule biguanide.
Siguiente paso
Siguiente paso: una consulta confidencial de 3 minutos, revisada por un profesional con licencia. No se promete ni se da a entender ningún tratamiento.
Gratis · unos 10 minutos · revisado por un médico con licencia
Educación general · No es consejo médico · Se requiere aprobación profesional